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FDA 2025 Animal Drug User Fee Educational Conference – Part 1



    Lesson Content:

    Opening Remarks

    Walt Ellenberg, Moderator
    Special Advisor
    Office of New Animal Drug Evaluation
    Center for Veterinary Medicine, FDA

    Welcome

    Matt Lucia
    Director
    Office of New Animal Drug Evaluation
    Center for Veterinary Medicine, FDA

    Meeting Overview

    Walt Ellenberg
    Special Advisor
    Office of New Animal Drug Evaluation
    Center for Veterinary Medicine, FDA

    Overview of User Fees and Waivers

    Aila Albrecht
    Office of New Animal Product Evaluation
    Center for Veterinary Medicine, FDA

    Jason Smith
    Office of New Animal Product Evaluation
    Center for Veterinary Medicine, FDA

    Foreign Data

    Ana Lazo
    Quality Assurance Specialist
    Office of New Animal Drug Evaluation
    Center for Veterinary Medicine, FDA

    Courtney Flick
    Office of New Animal Product Evaluation
    Center for Veterinary Medicine, FDA

    Brandi Robinson
    International Program Manager
    Office of New Animal Product Evaluation
    Center for Veterinary Medicine, FDA

    Abstract

    This webinar explores the US Food and Drug Administration’s (FDA) acceptance of foreign data in new animal drug approvals, emphasizing its role in supporting global approvals and minimizing duplicative studies. Foreign data, defined as information generated in studies conducted outside the United States, is acceptable for various technical sections, including target animal safety, effectiveness, and human food safety, helping to bridge gaps in US data. Key expectations for foreign data submissions include ensuring the same data quality and study integrity standards as domestic studies, proactive and early communication with CVM regarding study design and protocols, and a clear explanation of any deviations from US GLP regulations, along with an assessment of their impact. Common challenges encountered during review involve non-compliance with US GLP standards, issues with data measurement units, privacy concerns, inadequate personnel training documentation, and incomplete or inaccurate English translations of study records. To enhance the likelihood of foreign data acceptance, sponsors are encouraged to present data within the context of US approval, submit study protocols for CVM review, and actively engage in international collaboration programs. These collaborative opportunities, such as simultaneous reviews or parallel scientific advice, supported by international harmonization efforts and confidentiality agreements, proactively help ensure foreign studies can fulfill pivotal data requirements for FDA approval.

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