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Session 5B: Spotlight Generic Drug Review Challenges and Solutions



    Presentations

    Totality of Evidence Including Physiologically Based Pharmacokinetic (PBPK) Modeling to Support BE Assessment and Approval of Mesalamine Delayed Release Tablets

    Dr. Yang Lu
    Senior Staff Fellow
    Division of Bioequivalence III (DBIII)
    Office of Bioequivalence (OB)
    Office of Generic Drugs (OGD)
    Center for Drug Evaluation and Research (CDER)
    US Food and Drug Administration (FDA)

    Fang Wu, PhD
    Senior Pharmacologist
    Division of Quantitative Methods and Modeling (DQMM)
    Office of Research and Standards (ORS)
    Office of Generic Drugs (OGD)
    Center for Drug Evaluation and Research (CDER)
    US Food and Drug Administration (FDA)

    Challenges and Progress in Emerging Complex Generic Oligonucleotide Products

    Likan Liang, PhD
    Supervisory Chemist
    Division of Product Quality Assessment X (DPQA X)
    Office of Product Quality Assessment II (OPQA II)
    Office of Pharmaceutical Quality (OPQ)
    Center for Drug Evaluation and Research (CDER)
    US Food and Drug Administration (FDA)

    The Journey of First Approvals of Complex Generic Long-acting Injectable Products

    Yan Wang, PhD
    Lead Pharmacologist / Acting Deputy Division Director
    Division of Therapeutic Performance I (DTP-I)
    Office of Research and Standards (ORS)
    Office of Generic Drugs (OGD)
    Center for Drug Evaluation and Research (CDER)
    US Food and Drug Administration (FDA)

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